The ionozon Bath utilises ionized, nebulized water vapour in combination with ozonized oxygen (O3) or gaseous carbonic acid (CO2). Spraying in aerolizable active agents additionally offers the possibility of manifold balneological indications. The therapeutic effect of the nebulized oxygen-ozone bath is based on pure oxidation as well as on concentration of molecular oxygen in the nascent state in the tissue. As a result of the sterile condensate forming on the skin, active oxygen and oxygen diffuse deep into the tissue. In the venous blood, an increase in oxygen up to 25% is noted. The blood is de-acidified and the pH value normalized.